David Lynch directed four commercials for Calvin Klein Obsession and Obsession for Men in 1990. One of them featured Lara Flynn Boyle (of Twin Peaks!), but that one doesn’t appear to be on YouTube, unfortunately. Here are the other 3:
The new commercial for Gucci by Gucci, which opened Gucci's recent Spring & Summer collection at Milan's fashion week. It was directed by David Lynch and features Blondie's Heart of Glass. According to Frida Giannini, Gucci's Creative Director, "I wanted our first television advertising campaign to have that whimsical touch from a visionary film director such as David Lynch. I wanted him to capture the total essence of Gucci - and I'm thrilled with the result". (via vogue.co.uk)